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Chemical Attack
General Guidance
Be alert to the following:
Groups of individuals becoming ill around the same time
Sudden increase of illness in previously healthy individuals
Sudden increase in the following non-syndromes:
Sudden unexplained weakness in previously healthy individuals
Dimmed or blurred vision
Hypersecretion syndromes (like drooling, tearing, and diarrhea)
Inhalation syndromes (eye, nose, throat, chest irritation; shortness of breath)
Burn-like skin syndromes (redness, blistering, itching, sloughing)
Unusual temporal or geographic clustering of illness (for example, patients who attended the same public event, live in the same part of town, etc.)
Understanding exposure. Exposure may occur from vapor or liquid droplets and, less likely, contamination of food or water.
Chemical effects are dependent on:
volatility and amount of chemical
water solubility (higher solubility leads to more mucosal and less deep lung deposition and toxicity)
increased fat solubility and smaller molecular size increase skin absorption
Decontamination Considerations
Chemical warfare agents usually require removal of clothing and decontamination of the patient with soap and water.
Treating contaminated patients in the emergency department before decontamination may contaminate the facility.
Nerve Agents
Cyanide
Symptom Onset: seconds to minutes
Symptoms: almond-like smell
Moderate exposure: dizziness, nausea, headache, eye irritation
High exposure: loss of consciousness
Decontamination: clothing removal
Sulfur Mustard (blister agent)
Symptom Onset: 2 to 48 hours
Symptoms: skin erythema, blistering, conjunctivitis and lid swelling, upper airways sloughing, pulmonary edema, marrow suppression with hymphocytopenia
Decontamination: clothing removal, Large amounts of water
Phosgene (Pulmonary Agent)
Symptom Onset: 1 to 24 hours (rarely up to 72 hours)
Symptoms: shortness of breath, chest tightness, wheezing, mucosal and dermal irritation and redness
Decontamination: none usually needed
Ricin (castor bean toxin)
Symptom Onset: 18 to 24 hours
Ingestion: nausea, diarrhea, vomiting, fever, abdominal pain
Inhalation: chest tightness, coughing, weakness, nausea, fever
Decontamination: clothing removal, water rinse
T-2 (mycotoxin)
Symptom Onset: 2 to 4 hours
Symptoms: dermaland mucosal irritation, blistering, necrosis, blurred vision, eye irritation, nausea, vomiting and diarrhea, altaxia, coughing and dyspnea
Decontamination: clothing removal, water rinse
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