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Southern Tick-Associated Rash Illness


Southern Tick-Associated Rash Illness (STARI) was first recognized around the early 1990s when people began to show symptoms similar to Lyme disease. Unlike Lyme disease, these people did not have long-term problems, nor were they bitten by the same kind of tick (Ixodes scapularis or the black-legged tick). Studies have shown that the bacteria that causes Lyme disease, Borrelia burgdorferi, does not cause STARI. STARI may also be called "Masters disease" after the doctor who first identified the illness.

Lone star tick
STARI Transmission

Much about STARI is still unknown. The Centers for Disease Control and Prevention (CDC) have found that STARI usually occurs after a bite from an infected lone star tick (Amblyomma americanum). The specific organism that an infected lone star tick carries is not known. However, a bacterium called Borrelia lonestari has been discovered and may be a possible cause, but more research is needed. Lone star ticks live in the southeast and as far north as Maine. Adult females have a white "lone star" on their backs. These ticks seek out and bite people during any of their three life stages - larvae, nymph, or adult. Lone star ticks can also transmit other diseases.                                                                                  
                                                                                                                                                                                       Photo of A. americanum courtesy of CDC

Symptoms and Treatment

The most obvious sign of a STARI infection is a rash called erythema migrans (EM), which has the shape of a "bull's eye". This symptom is often confused with Lyme disease, which has a similar or identical rash. The rash can bee seen about seven days after the tick bite, and expands outward from the site of the bite. There may be a central area of clear skin. Other signs can include tiredness, fever, headaches, muscle and joint pain. STARI differs from Lyme disease in that arthritic, neurological, and recurring symptoms do not develop as the disease gets worse. According to past and recent studies on STARI, patients recover quickly from the rash and other symptoms after treatment with oral antibiotics.

Lone star tickPatient with STARI; 1) site of tick bite,
2) red, radial, expanding edge of rash,
3) central clearing. Photo courtesy of CDC.


 

 

 

Map of A. americanum distribution, courtesy of CDC.Lone star tick

STARI in Florida

STARI has been discovered in Florida and research on the occurrence of the disease is underway. However, it may take some time before all the necessary information can be collected since much is still unknown about STARI.


CDC Research on STARI

The Centers for Disease Control and Prevention (CDC) is requesting participation in a study to ascertain if a Borrelia organism    other than B. burgdorferi is causing Lyme-like disease, Southern Tick-Associated Rash Illness (STARI), in southern states. Physicians are encouraged to contact the CDC if a patient develops an expanding rash (5 cm or more in diameter) after a recent lone star tick bite. Included below are the CDC letters of explanation to physicians and their patients interested in participating in this study.


Prevention of Tick-borne Diseases


Resources

1) Little, Susan. Southern tick-associated rash illness: A newly recognized tick-borne disease. DVM Newsmagazine: Best Practices 2003.

2) Centers for Disease Control and Prevention (CDC) Southern Tick-Associated Rash Illness. www.cdc.gov/ncidod/dvbid/stari/

3) Wilderness Medical Society (WMS) Southern Tick-Associated Rash Illness. www.wms.org/Updates/STARI1.htm

4) Purdue University Medical Entomology Department: STARI (Southern Tick-Associated Rash Illness) www.entm.perdue.edu/publichealth/diseases/tick/stari.html
 


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